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✪ Structural readiness to implement community-wide mass drug administration programs for soil-transmitted helminth elimination: results from a three-country hybrid study

Authors:

Arianna Rubin Means, Elizabeth Orlan, Marie-Claire Gwayi-Chore, Angelin Titus, Saravanakumar Puthupalayam Kaliappan, Comlanvi Innocent Togbevi, Félicien Chabi, Katherine E. Halliday, Providence Nindi, Euripide Avokpaho, Khumbo Kalua, Moudachirou Ibikounlé, Sitara S. R. Ajjampur, Bryan J. Weiner, Judd L. Walson, & Kumudha Aruldas

University of Washington affiliated authors are displayed in bold.

✪ Open Access

Published: July 2021

Read the full text in the open access journal Implementation Science Communications

Abstract:

Background

Current soil-transmitted helminth (STH) control programs target pre-school and school-age children with mass drug administration (MDA) of deworming medications, reducing morbidity without interrupting ongoing transmission. However, evidence suggests that STH elimination may be possible if MDA is delivered to all community members. Such a change to the STH standard-of-care would require substantial systems redesign. We measured baseline structural readiness to launch community-wide MDA for STH in Benin, India, and Malawi.

Methods

After field piloting and adaptation, the structural readiness survey included two constructs: Organizational Readiness for Implementing Change and Organizational Capacity for Change. Sub-constructs of organizational readiness include change commitment and change efficacy. Sub-constructs of organizational capacity include flexibility, organizational structure, and demonstrated capacity. Survey items were also separately organized into seven implementation domains. Surveys were administered to policymakers, mid-level managers, and implementers in each country using a five-point Likert scale. Item, sub-construct, construct, and domain-level medians and interquartile ranges were calculated for each stakeholder level within each country.

Results

Median organizational readiness for change scores were highest in Malawi (5.0 for all stakeholder groups). In India, scores were 5.0, 4.0, and 5.0 while in Benin, scores were 4.0, 3.0, and 4.0 for policymakers, mid-level managers, and implementers, respectively. Median change commitment was equal to or higher than median change efficacy across all countries and stakeholder groups.

Median organizational capacity for change was highest in India, with a median of 4.5 for policymakers and mid-level managers and 5.0 for implementers. In Malawi, the median capacity was 4.0 for policymakers and implementers, and 3.5 for mid-level managers. In Benin, the median capacity was 4.0 for policymakers and 3.0 for mid-level managers and implementers. Median sub-construct scores varied by stakeholder and country.

Across countries, items reflective of the implementation domain ‘policy environment’ were highest while items reflective of the ‘human resource’ domain were consistently lower.

Conclusion

Across all countries, stakeholders valued community-wide MDA for STH but had less confidence in their collective ability to effectively implement it. Perceived capacity varied by stakeholder group, highlighting the importance of accounting for multi-level stakeholder perspectives when determining organizational preparedness to launch new public health initiatives.

Trial registration

NCT03014167

**This abstract is posted with permission under the Creative Commons Attribution 4.0 International License**

✪ Phased Implementation of COVID-19 Vaccination: Rapid Assessment of Policy Adoption, Reach and Effectiveness to Protect the Most Vulnerable in the US

Authors:

Yun Li, Moming Li, Megan Rice, Yanfang Su, and Chaowei Yang

University of Washington affiliated authors are displayed in bold.

✪ Open Access

Published: July 2021

Read the full text in the open access International Journal of Environmental Research and Public Health

Abstract:

The US and the rest of the world have suffered from the COVID-19 pandemic for over a year. The high transmissibility and severity of this virus have provoked governments to adopt a variety of mitigation strategies. Some of these previous measures, such as social distancing and mask mandates, were effective in reducing the case growth rate yet became economically and administratively difficult to enforce as the pandemic continued. In late December 2020, COVID-19 vaccines were first approved in the US and states began a phased implementation of COVID-19 vaccination. However, there is limited quantitative evidence regarding the effectiveness of the phased COVID-19 vaccination. This study aims to provide a rapid assessment of the adoption, reach, and effectiveness of the phased implementation of COVID-19 vaccination. We utilize an event-study analysis to evaluate the effect of vaccination on the state-level daily COVID-19 case growth rate. Through this analysis, we assert that vaccination was effective in reducing the spread of COVID-19 shortly after the first shots were given. Specifically, the case growth rate declined by 0.124, 0.347, 0.345, 0.464, 0.490, and 0.756 percentage points corresponding to the 1–5, 6–10, 11–15, 16–20, 21–25, and 26 or more day periods after the initial shots. The findings could be insightful for policymakers as they work to optimize vaccine distribution in later phases, and also for the public as the COVID-19 related health risk is a contentious issue.

**This abstract is posted with permission under the Creative Commons Attribution 4.0 International License**

✪ The Cognitive Walkthrough for Implementation Strategies (CWIS): a pragmatic method for assessing implementation strategy usability

Authors:

Aaron R. Lyon, Jessica Coifman, Heather Cook, Erin McRee, Freda F. Liu, Kristy Ludwig, Shannon Dorsey, Kelly Koerner, Sean A. Munson, & Elizabeth McCauley

University of Washington affiliated authors are displayed in bold.

✪ Open Access

Published: July 2021

Read the full text in the open access journal Implementation Science Communications

Abstract:

Background

Implementation strategies have flourished in an effort to increase integration of research evidence into clinical practice. Most strategies are complex, socially mediated processes. Many are complicated, expensive, and ultimately impractical to deliver in real-world settings. The field lacks methods to assess the extent to which strategies are usable and aligned with the needs and constraints of the individuals and contexts who will deliver or receive them. Drawn from the field of human-centered design, cognitive walkthroughs are an efficient assessment method with potential to identify aspects of strategies that may inhibit their usability and, ultimately, effectiveness. This article presents a novel walkthrough methodology for evaluating strategy usability as well as an example application to a post-training consultation strategy to support school mental health clinicians to adopt measurement-based care.

Method

The Cognitive Walkthrough for Implementation Strategies (CWIS) is a pragmatic, mixed-methods approach for evaluating complex, socially mediated implementation strategies. CWIS includes six steps: (1) determine preconditions; (2) hierarchical task analysis; (3) task prioritization; (4) convert tasks to scenarios; (5) pragmatic group testing; and (6) usability issue identification, classification, and prioritization. A facilitator conducted two group testing sessions with clinician users (N = 10), guiding participants through 6 scenarios and 11 associated subtasks. Clinicians reported their anticipated likelihood of completing each subtask and provided qualitative justifications during group discussion. Following the walkthrough sessions, users completed an adapted quantitative assessment of strategy usability.

Results

Average anticipated success ratings indicated substantial variability across participants and subtasks. Usability ratings (scale 0–100) of the consultation protocol averaged 71.3 (SD = 10.6). Twenty-one usability problems were identified via qualitative content analysis with consensus coding, and classified by severity and problem type. High-severity problems included potential misalignment between consultation and clinical service timelines as well as digressions during consultation processes.

Conclusions

CWIS quantitative usability ratings indicated that the consultation protocol was at the low end of the “acceptable” range (based on norms from the unadapted scale). Collectively, the 21 resulting usability issues explained the quantitative usability data and provided specific direction for usability enhancements. The current study provides preliminary evidence for the utility of CWIS to assess strategy usability and generate a blueprint for redesign.

**This abstract is posted with permission under the Creative Commons Attribution 4.0 International License**

✪ The relationship between first-level leadership and inner-context and implementation outcomes in behavioral health: a scoping review

Authors:

Rosemary D. Meza, Noah S. Triplett, Grace S. Woodard, Prerna Martin, Alya N. Khairuzzaman, Gabrielle Jamora, & Shannon Dorsey

University of Washington affiliated authors are displayed in bold.

✪ Open Access

Published: July 2021

Read the full text in the open access journal Implementation Science

Abstract:

Background

First-level leadership is uniquely positioned to support evidence-based practice (EBP) implementation for behavioral health due to first-level leaders’ access to and relationship with service providers. First-level leaders are individuals who directly supervise and manage frontline employees who do not manage others. However, first-level leadership is underrepresented in existing reviews of the impact of leadership on EBP implementation. This review describes the relationship between first-level leadership and implementation determinants and outcomes.

Methods

A scoping review was performed to synthesize the literature on the relationship between first-level leadership and inner-context and implementation outcomes. A literature search was conducted in PubMed, Eric, PsycINFO, CINAHL, Scopus, and Web of Science. To be eligible, studies had to examine first-level leadership, be conducted in settings providing behavioral health services, and examine the relationship between first-level leadership and an implementation or inner-context outcome. Data extraction and synthesis were performed to describe study characteristics, leader-outcome relationships, and overlap in leadership frameworks.

Results

Twenty-one records met our inclusion criteria. Studies primarily relied on observational designs and were often cross-sectional. Studies more often examined general leadership rather than leadership strategically focused on EBP implementation (i.e., strategic implementation leadership). Our findings suggest that several forms of first-level leadership are inconsistently related to a broad set of implementation determinants, with infrequent examination of specific implementation outcomes. The broad set of implementation determinants studied, limited number of replications, and inconsistent findings have resulted in sparse evidence for any specific leadership-outcome relationship. The greatest accumulation of evidence exists for general leadership’s positive relationship with providers’ EBP attitudes, most notably in the form of transformational leadership. This was followed by evidence for strategic implementation leadership facilitating general implementation. Our synthesis revealed moderate conceptual overlap of strategic implementation leadership behaviors described in the theory of implementation leadership and theory of middle managers’ role in implementation.

Conclusions

Our findings suggest that first-level leadership may play an important role in shaping implementation determinants and outcomes, but consistent empirical support is sparse and confidence dampened by methodological issues. To advance the field, we need studies that adopt stronger methodological rigor, address the conceptual overlap in leadership frameworks, examine a broader set of implementation outcomes, and examine conditions under which leadership impacts implementation.

**This abstract is posted with permission under the Creative Commons Attribution 4.0 International License**

Male Caregiver Barriers to HIV Index Case Testing of Untested Children

Authors:

Jillian Neary, Anjuli D Wagner, Vincent Omondi, Verlinda Otieno, Cyrus Mugo, Dalton C Wamalwa, Elizabeth Maleche-Obimbo, Grace C John-Stewart, Jennifer A Slyker, & Irene N Njuguna

University of Washington affiliated authors are displayed in bold.

Subscription Required for Full Text Access

Published: July 2021

Read the full text in the subscription access Journal of Acquired Immune Deficiency Syndrome

✪ Building Implementation Science Capacity in Academic Pharmacy: Report of the 2020-2021 AACP Research and Graduate Affairs Committee

Authors:

Kimberly B. Garza, Ephrem Abebe, Jennifer L. Bacci, Nitesh K. Kunda, Kajua B. Lor, Nathaniel Rickles, Nathan Shankar, and Dorothy Farrell

University of Washington affiliated authors are displayed in bold.

✪ Open Access

Published: July 2021

Read the full text in the American Journal of Pharmaceutical Education

Abstract:

Executive Summary

The 2020-2021 AACP Research and Graduate Affairs Committee (RGAC) continued the work begun by the 2019-2020 RGAC to increase awareness of and capacity for implementation research to advance practice transformation in academic pharmacy. AACP President Anne Lin charged the RGAC with developing resources and programs for training faculty and graduate students in implementation science. The committee was further charged with developing a mechanism to pair pharmacy faculty and implementation experts on practice advancement projects. In its work, the committee focused on generating near-term opportunities for pharmacy practice faculty to pursue projects while developing programs that would support ongoing career development and future implementation practice and research by pharmacy faculty and trainees.

To support training, the RGAC developed a competency framework for graduate education that builds on the six domains of graduate education in pharmaceutical sciences put forward by the 2016-2017 RGAC. The new, specialized framework identifies and organizes those competencies that should be cultivated to successfully pursue implementation research in pharmacy, with utility beyond graduate education. The identified competencies could act as the base for pharmacy-specific implementation science training materials suitable for faculty development. The committee proposes a faculty development program that leverages the framework and existing implementation science training resources offered by federal agencies and universities to provide facilitated learning opportunities and peer support for faculty who wish to pursue implementation research.

The committee considered multiple approaches AACP could take to promote collaboration between pharmacy faculty and implementation experts. While recognizing the importance of individual development support for pharmacy faculty, the committee felt that a focus on supporting interdisciplinary teams that span practice and research and engage faculty, trainees and preceptors would have the greatest impact on enabling practice advancement projects in the near term while increasing capacity in the long-term. The committee envisions a program in which AACP creates opportunities for pharmacy faculty and implementation experts to come together with the purpose of matching researchers and projects. AACP support for these collaborations should begin prior to any such matching event, for example by helping pharmacy faculty articulate the scope and value of their proposed practice advancement projects, and extend beyond the initial match to include assisting nascent collaborations establish connections and secure institutional and external backing.

The RGAC made specific recommendations to AACP about how the framework and proposed programs could be used to further develop pharmacy faculty and graduate students as researchers while advancing the goal of sustainable transformation of pharmacy practice. A key recommendation is that AACP cultivate an inclusive community of interest in implementation science in pharmacy that will promote adoption of the framework, act as facilitators and coaches for training programs and assist in planning and supporting collaborative research projects.

Expected Organizational Costs for Inserting Prevalence Information Into Lumbar Spine Imaging Reports

Authors:

Brian W. Bresnahan, Jeffrey G. Jarvik, Eric N. Meier, Kathryn T. James, Laura S. Gold, Sean D. Rundell, Judith A. Turner, Pradeep Suri, Patrick H. Luetmer, Janna L. Friedly, Karen J. Sherman,
Patrick J. Heagerty, David F. Kallmes, Andrew L. Avins, Brent D. Griffith, & Larry G. Kessler

University of Washington affiliated authors are displayed in bold.

Subscription Required for Full Text Access

Published: June 2021

Read the full text in the subscription access Journal of the American College of Radiology

Financial Incentives for Pediatric HIV Testing (FIT): Caregiver Insights on Incentive Mechanisms, Focus Populations, and Acceptability for Programmatic Scale Up

Authors:

Junyi Zhang, Dana L. Atkins, Anjuli D. Wagner, Irene N. Njuguna, Jillian Neary, Vincent O. Omondi, Verlinda A. Otieno, Winnie O. Atieno, Merceline Odhiambo, Dalton C. Wamalwa, Grace John-Stewart, Jennifer A. Slyker, Bryan J. Weiner, & Kristin Beima-Sofie

University of Washington affiliated authors are displayed in bold.

Subscription Required for Full Text Access

Published: June 2021

Read the full text in the subscription access journal AIDS and Behavior