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Topics in implementation science

Digging deeper to bridge the gap

This page is designed to provide you with essential resources on key topics in implementation science, from adaptation to sustainability.

Implementation science is a critical field that bridges the gap between research and practice, ensuring that evidence-based interventions and practices are effectively integrated into real-world settings. Understanding these key topics is vital for anyone involved in the implementation process, as they drive, address, or exacerbate the various challenges and opportunities that arise when applying research findings in differing environments. Below you will find resources on:

Adaptation: The process of modifying interventions to fit the specific needs and contexts of different settings without compromising their core components.

Community and Stakeholder Engagement: The involvement of community members and stakeholders in the research process to ensure that interventions are relevant, culturally appropriate, and more likely to be adopted and sustained.

Context: The various factors and conditions that influence the implementation of interventions, including social, cultural, economic, political, and institutional environments.

Deimplementation: The process of reducing or stopping the use of interventions that are ineffective, inappropriate, or harmful.

Fidelity: The degree to which an intervention is delivered as intended by its developers. High fidelity ensures that the intervention maintains its intended effects.

Health Equity: Ensuring that interventions and implementation strategies are designed and implemented in ways that address disparities and promote equitable health outcomes for all populations.

Sustainability: The ability to maintain the benefits of an intervention over the long term, ensuring that positive outcomes continue even after initial funding and support have ended.

Sustainment: The actual continued use of an intervention over time.

Usability: The ease with which an intervention can be used by its intended users to achieve specific goals effectively, efficiently, and satisfactorily.

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Each section of this page provides a brief introduction to these topics and a curated list of free online resources to help you learn more. Whether you are a researcher, practitioner, or student, these resources will equip you with the knowledge and tools needed to navigate the complexities of implementation science and enhance the impact of your work. Explore the sections below to deepen your understanding and access useful materials that will support your journey in learning more about implementation science.

Adaptation

Adaptation in implementation science refers to the process of making thoughtful and deliberate changes to the design or implementation of an intervention to improve its fit or effectiveness within a specific context. This concept is crucial because it acknowledges that interventions often need to be tailored to better align with the unique characteristics of different settings, populations, or circumstances. Adaptations can be planned and proactive, aiming to enhance the intervention’s or strategy’s relevance and impact, or they can be unplanned and reactive, addressing unforeseen challenges that arise during implementation.

When adapting the intervention, the goal is to modify its components to better fit the specific context or population while maintaining its core elements. This might involve altering the content, delivery methods, or materials used in the intervention. On the other hand, adapting the implementation strategy involves modifying the methods and processes used to deliver the intervention. This could include changes to training protocols, support systems, or the way the intervention is integrated into existing workflows. Both types of adaptations are crucial for achieving the desired outcomes and ensuring that the intervention can be successfully implemented and sustained over time. Understanding when and how to make these adaptations, and evaluating their impact, is a key area of focus in implementation science.

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The Framework for Reporting Adaptations and Modifications to Evidence-based Implementation Strategies (FRAME-IS) is a tool designed to systematically document changes made to implementation strategies. This framework is particularly relevant in the field of implementation science, where understanding and tracking adaptations is crucial for ensuring the effectiveness and sustainability of interventions.

FRAME-IS helps researchers and practitioners capture detailed information about what modifications are made, the nature of these modifications, the rationale behind them, and their timing. It also documents who is involved in the decision-making process and how widespread the modifications are. By providing a structured approach to recording these changes, FRAME-IS aims to illuminate the processes and mechanisms by which implementation strategies exert their effects, thereby enhancing the overall understanding of how and why adaptations occur.

This framework is essential for studying adaptation in implementation science because it allows for a more precise and comprehensive understanding of how interventions are tailored to fit different contexts. By systematically documenting adaptations, FRAME-IS supports the evaluation of their impact on fidelity and outcomes, helping to identify best practices for modifying implementation strategies to improve their fit and effectiveness in diverse settings. To learn more, read The FRAME-IS: a framework for documenting modifications to implementation strategies in healthcare, open access in the journal Implementation Science.

Community & Stakeholder Engagement

Community and stakeholder engagement in implementation science is the process of actively involving the people and groups who are affected by or have an interest in the intervention being implemented. This approach is essential for ensuring that interventions are relevant, acceptable, and sustainable within the target community. Engaging stakeholders, which can include community members, healthcare providers, policymakers, and other relevant parties, helps to build trust, foster collaboration, and ensure that diverse perspectives are considered throughout the implementation process.

This engagement can take various forms, such as participatory action research, where stakeholders are involved in all stages of the research process, from identifying the problem to designing and implementing the intervention, and disseminating the findings. By involving stakeholders in this way, implementation science aims to create interventions that are more likely to be effective and sustainable because they are tailored to the specific needs and contexts of the community.

Moreover, community and stakeholder engagement helps address potential barriers to implementation by identifying and responding to concerns early in the process. It also promotes a sense of ownership and empowerment among community members, which can enhance the uptake and long-term success of the intervention. Overall, this approach is about creating a partnership between researchers and the community to ensure that the interventions are not only evidence-based but also contextually appropriate and supported by those who will be most affected by them.

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Context

Context is the various factors and conditions that influence the implementation of interventions in real-world settings. These factors can include the social, cultural, economic, political, legal, and physical environments, as well as the institutional settings where the interventions are applied. Context encompasses the interactions among stakeholders, the demographic and epidemiological conditions, and the resources available for implementation.

Implementation science often splits context into two categories: inner context or outer context (also sometimes referred to as internal context and external context). Inner context refers to factors within the organization or setting where the intervention is being implemented. This includes the organizational culture, leadership, staff attitudes, and available resources. Internal context can be further divided into micro-level (individuals or teams) and meso-level (organizational units or departments) factors. Outer context encompasses broader socio-economic, political, and environmental factors that influence implementation but are beyond the control of the organization. This includes policies, regulations, funding environments, and community characteristics.

Understanding context is crucial because it affects how interventions are adopted, adapted, and sustained. It includes the organizational support, financial resources, social relations, leadership, and other dimensions that can either facilitate or hinder the implementation process. Researchers must consider these contextual elements to design effective interventions and ensure they are adaptable to different settings. By acknowledging and addressing context, implementation science aims to bridge the gap between controlled research environments and the complex realities of practical application, ultimately improving the effectiveness and sustainability of health interventions.

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Context matters in implementation science: a scoping review of determinant frameworks that describe contextual determinants for implementation outcomes (BMC Health Services Research, 2019)

Understanding dynamic complexity in context—Enriching contextual analysis in implementation science from a constructivist perspective (Frontiers in Health Services, 2022)

Connecting the science and practice of implementation – applying the lens of context to inform study design in implementation research (Frontiers in Health Services, 2023)

Context in Implementation Science (Pediatrics, 2022)

Forms and functions of bridging factors: specifying the dynamic links between outer and inner contexts during implementation and sustainment (Implementation Science, 2021)

How does the external context affect an implementation processes? A qualitative study investigating the impact of macro-level variables on the implementation of goal-oriented primary care (Implementation Science, 2024)

Development of an integrative coding framework for evaluating context within implementation science (BMC Medical Research Methodology, 2020)

Methodological approaches to study context in intervention implementation studies: an evidence gap map (BMC Medical Research Methodology, 2022)

Unraveling implementation context: the Basel Approach for coNtextual ANAlysis (BANANA) in implementation science and its application in the SMILe project (Implementation Science Communications, 2022)

Ethnography and user-centered design to inform context-driven implementation (Translational Behavioral Medicine, 2022)

Deimplementation

Deimplementation is the process of reducing or stopping the use of interventions, practices, or policies that are ineffective, inappropriate, or potentially harmful. This concept is crucial because it ensures that resources are not wasted on interventions that do not provide the intended benefits or may even cause harm. Deimplementation involves identifying these interventions through rigorous evaluation and then systematically phasing them out in favor of more effective alternatives.

The process of deimplementation can be complex, as it often requires overcoming resistance from stakeholders who may be accustomed to the existing practices. It involves careful planning, communication, and support to ensure that the transition is smooth and that the new, more effective interventions are successfully adopted. By focusing on deimplementation, researchers and practitioners can improve the overall quality of care and ensure that the best possible interventions are being used in practice. This approach not only enhances the effectiveness of health interventions but also promotes the efficient use of resources and supports the continuous improvement of healthcare systems.

Fidelity

Fidelity refers to the degree to which an intervention or strategy is delivered as intended by the developers. It encompasses several dimensions, including adherence to the intervention’s core components, the quality of delivery, and the extent to which the intervention is implemented consistently across different settings and practitioners.

High fidelity is crucial because it ensures that the intervention is being executed as designed, which is necessary to accurately assess its effectiveness and to replicate successful outcomes in different contexts. Fidelity also involves monitoring and evaluating the implementation process to identify any deviations or adaptations that may occur and understanding how these changes impact the overall effectiveness of the intervention.

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Health Equity

In the field of implementation science and implementation research, health equity refers to the principle and goal of ensuring that all individuals have fair and just access to healthcare services and interventions, regardless of their socioeconomic status, race, ethnicity, gender, or other social determinants. It involves identifying and addressing disparities in health outcomes and healthcare access that are often rooted in systemic inequalities and social injustices.

Health equity aims to eliminate these disparities by tailoring interventions and implementation strategies to meet the specific needs of marginalized and underserved populations, ensuring that everyone has the opportunity to achieve optimal health. This requires a deliberate focus on integrating equity considerations into all stages of the implementation process, from the design and selection of interventions to their implementation and evaluation, to ensure that the benefits of healthcare innovations are equitably distributed and sustained over time.

Below, find resources on health equity in implementation science, anti-racist research & studying impacts of racism, decolonizing global health, and cultural adaptation.

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Journal Articles & Blog Posts
Health Equity in Implementation Science

Equity in Implementation Science Is Long Overdue (Stanford Social Innovation Review, 2021)

Advancing health equity through a theoretically critical implementation science (Translational Behavioral Medicine, 2021)

Grounding implementation science in health equity for cancer prevention and control (Implementation Science Communications, 2022)

Situating implementation science (IS) in res(IS)tance: a conceptual frame toward the integration of scholarship from the black radical tradition (Frontiers in Public Health, 2024)

Using Participatory Implementation Science to Advance Health Equity (Annual Review of Public Health, 2024)

Five Recommendations for How Implementation Science Can Better Advance Equity (AcademyHealth, 2019)

Implementation science should give higher priority to health equity (Implementation Science, 2021)

A scoping review of equity-focused implementation theories, models and frameworks in healthcare and their application in addressing ethnicity-related health inequities (Implementation Science, 2023)

Cost—A Hidden Aspect of Equity-Grounded Implementation Science (JAMA Forum, 2024)

Equitable Implementation at Work (Stanford Social Innovation Review, 2021)

Applying an equity lens to assess context and implementation in public health and health services research and practice using the PRISM framework (Frontiers in Health Services, 2023)

Global, Regional, National, and Subnational Big Data to Inform Health Equity Research: Perspectives from the Global Burden of Disease Study 2017 (Ethnicity & Disease, 2019)

Perspective: Social Determinants of Health and Implementation Research: Lessons from the COVID-19 Pandemic (Ethnicity & Disease, 2021)

Are we being equitable enough? Lessons learned from sites lost in an implementation trial (Implementation Research and Practice, 2024)

Advancing healthcare equity through dissemination and implementation science (Health Services Research, 2023)

Enhancing Impact: A Call to Action for Equitable Implementation Science (Prevention Science, 2023)

Anti-Racist Research & Studying Impacts of Racism

Application of an antiracism lens in the field of implementation science (IS): Recommendations for reframing implementation research with a focus on justice and racial equity (Implementation Research and Practice, 2021)

Recommendations for Addressing Structural Racism in Implementation Science: A Call to the Field (Ethnicity & Disease, 2021)

Recommendations for Using Causal Diagrams to Study Racial Health Disparities (American Journal of Epidemiology, 2022)

Applying a Race(ism)-Conscious Adaptation of the CFIR Framework to Understand Implementation of a School-Based Equity-Oriented Intervention (Ethnicity & Disease, 2021)

Rationale for the Design and Implementation of Interventions Addressing Institutional Racism at a Local Public Health Department (Ethnicity & Disease, 2021)

Antiracism and Health Equity Science: Overcoming Scientific Obstacles to Health Equity (Public Health Reports, 2024)

Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions (American Journal of Public Health (AJPH), 2023)

Extending critical race, racialization, and racism literatures to the adoption, implementation, and sustainability of data equity policies and data (dis)aggregation practices in health research (Health Services Research, 2023)

Decolonizing Global Health

Diversifying Implementation Science: A Global Perspective (Global Health: Science and Practice, 2022)

A proposed guide to reducing bias and improving assessments of decolonization in global health research (Frontiers in Education, 2024)

Challenges and Opportunities for Paving the Road to Global Health Equity Through Implementation Science (Annual Review of Public Health, 2024)

Decolonizing Global Health (Continued)

Decolonizing Global Health: A Moment To Reflect On A Movement (Forbes, 2021)

Report: Time to Decolonise Aid (Adesco, Alliance for Peacebuilding, Peace Direct, WCAPS, Women of Color Advancing Peace, Security and Conflict Transformation, 2021)

Cultural Adaptation

A two-way street: bridging implementation science and cultural adaptations of mental health treatments (Implementation Science, 2013)

The Cultural Adaptation Checklist (CAC): quality indicators for cultural adaptation of intervention and practice (International Journal of Developmental Disabilities, 2023)

Model of engaging communities collaboratively: Working towards an integration of implementation science, cultural adaptation and engagement (International Journal of Critical Indigenous Studies, 2020)

Barriers, frameworks, and mitigating strategies influencing the dissemination and implementation of health promotion interventions in indigenous communities: a scoping review (Implementation Science, 2022)

Cultural adaptations and cultural factors in EBI implementation with Latinx communities (Frontiers in Public Health, 2023)

Advances in the adaptation and implementation of evidence-based interventions for historically marginalized groups (Behaviour Research and Therapy, 2023)

Collections, Training, & Websites

💻 The Campbell and Cochrane Equity Methods Group (Cochrane and Campbell Collaboration)

💻 Cochrane Methods – Health Equity: Training & Webinars (Cochrane and Campbell Collaboration)

💻 CDC Health Equity Research Guide (United States Centers for Disease Control and Prevention)

💻 CMS Framework for Health Equity (United States Centers for Medicare & Medicaid Services)

💻 Conducting research through an anti-racism lens (University of Minnesota)

💻 Race and Equity Initiative: Anti-racism resources (University of Washington)

💻 Resources on Racism and Health (HealthAffairs)

Videos & Podcasts

🎧 Pathways to Accelerate Health Equity: A Health Systems Podcast (U.S. Agency for International Development)

🎧 That Implementation Science Podcast: Implementation in Low Resource and International Settings, with guest Shannon Dorsey, PhD

🎥 Examination of Structural Racism & Social Determinants of Health to Advance Health Equity through IS (National Cancer Institute)

🎥 Joining Forces: Engagement Science and Implementation Science to Advance Health Equity (National Cancer Institute)

🎥 Health Disparities and Implementation Science: Implications and Opportunities (National Cancer Institute)

🎥 TIDIRC: Exploring Health Equity in Implementation Science (National Cancer Institute)

🎥 Framing Priorities for Advancing Health Equity through Implementation Science (National Cancer Institute)

🎥 Implementation Science: Context & Equity in Cancer Research (National Cancer Institute)

🎥 Implementation Science Series on Health & Equity (Columbia University)

🎥 Inclusive language in scientific publishing: Race, ethnicity, and ancestry (Cell Press)

Sustainability & Sustainment

Sustainability refers to the extent to which an evidence-based intervention continues to be delivered and maintains its intended benefits over an extended period of time. This concept involves not only the ongoing use of the intervention but also its ability to adapt and evolve while still achieving positive outcomes. Sustainability is crucial because it ensures that the benefits of an intervention are not short-lived but are instead integrated into regular practice, leading to lasting improvements in health or other targeted outcomes. It also involves understanding and addressing the factors that influence the continued use and effectiveness of the intervention, such as organizational support, funding, and the adaptability of the intervention to changing contexts.

Sustainment, a related concept, refers to the continued use of an intervention over time, ensuring it remains effective and integrated into routine practice. Unlike sustainability, which broadly considers the long-term viability of an intervention, sustainment focuses specifically on maintaining the fidelity and effectiveness of the intervention within the service setting. This involves ongoing support, adaptation to changing contexts, and continuous monitoring to ensure the intervention continues to deliver its intended benefits. Sustainment is crucial for achieving lasting impact and requires addressing various factors such as organizational commitment, funding stability, and the ability to adapt to new challenges.

Accessible Accordion

Developing a comprehensive definition of sustainability (Implementation Science, 2017)

Sustaining the Implementation of Evidence-Based Interventions in Clinical and Community Settings (Frontiers in Health Services, 2023)

Assessing the sustainability capacity of evidence-based programs in community and health settings (Frontiers in Health Services, 2022)

Do the Expert Recommendations for Implementing Change (ERIC) strategies adequately address sustainment? (Frontiers in Health Services, 2022)

An initial typology of approaches used by policy and practice agencies to achieve sustained implementation of interventions to improve health (Implementation Science Communications, 2024)

Navigating the sustainability landscape: a systematic review of sustainability approaches in healthcare (Implementation Science, 2018)

Toward the sustainability of health interventions implemented in sub-Saharan Africa: a systematic review and conceptual framework (Implementation Science, 2016)

Evaluation of measures of sustainability and sustainability determinants for use in community, public health, and clinical settings: a systematic review (Implementation Science, 2022)

Adaptability, Scalability and Sustainability (ASaS) of complex health interventions: a systematic review of theories, models and frameworks (Implementation Science, 2024)

Provider REport of Sustainment Scale (PRESS): development and validation of a brief measure of inner context sustainment (Implementation Science, 2021)

Integrating the Practical Robust Implementation and Sustainability Model With Best Practices in Clinical Decision Support Design: Implementation Science Approach (Journal of Medical Internet Research, 2020)

💻 A Conversation about the Sustainability of Health Interventions (National Cancer Institute)

💻 Building a Lasting Impact: Implementation Science and Sustainability (National Cancer Institute)

💻 Video Series on Sustainability (Dr. Rachel Shelton, ScD, MPH)

Usability

Usability refers to the extent to which an intervention or implementation strategy can be used by specified individuals to achieve specific goals effectively, efficiently, and satisfactorily within a particular context. It involves assessing how easy and practical it is for users to adopt and integrate the intervention into their routine practices. High usability is desirable because it directly impacts the likelihood of successful implementation and sustained use of the intervention.

Factors influencing usability include the clarity of instructions, the complexity of the intervention, the support provided to users, and the adaptability of the intervention to different settings and user needs. Ensuring high usability often involves iterative testing and refinement based on user feedback to address any barriers and enhance the overall user experience.

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The Cognitive Walkthrough for Implementation Strategies (CWIS): a pragmatic method for assessing implementation strategy usability (Implementation Science Communications, 2021)

Usability Evaluation for Evidence-Based Psychosocial Interventions (USE-EBPI): A methodology for assessing complex intervention implementability (Implementation Research and Practice, 2020)

Assessing the usability of complex psychosocial interventions: The Intervention Usability Scale (Implementation Research and Practice, 2021)

Usability Issues in Evidence-Based Psychosocial Interventions and Implementation Strategies: Cross-project Analysis (Journal of Medical Internet Research, 2022)

Applying cognitive walkthrough methodology to improve the usability of an equity-focused implementation strategy (Implementation Science Communications , 2024)

Aligning implementation and user-centered design strategies to enhance the impact of health services: results from a concept mapping study (Implementation Science Communications, 2020)

Implementing Technologies to Enhance Coordinated Specialty Care Framework: Implementation Outcomes from a Development and Usability Study (JMIR Formative Research, 2023)

Harmonizing evidence-based practice, implementation context, and implementation strategies with user-centered design: a case example in young adult cancer care (Implementation Science Communications, 2021)

Implementation Strategy Usability Scale (UW ALACRITY Center)

System Usability Scale (UW ALACRITY Center)